{"product_id":"kcnab1-polyclonal-antibody-e-ab-91124","title":"KCNAB1 Polyclonal Antibody - E-AB-91124","description":"\u003cp\u003eKCNAB1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91124-60, E-AB-91124-120, E-AB-91124-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KCNAB1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: KCNAB1; AKR6A3; KCNA1B; KV-BETA-1; Kvb1.3; hKvBeta3; hKvb3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q14722\u003c\/p\u003e\n\n\u003cp\u003eBackground: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human KCNAB1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44kDa\/45kDa\/46kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 45-50kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146592092339,"sku":"E-AB-91124-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146592125107,"sku":"E-AB-91124-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146592157875,"sku":"E-AB-91124-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_58e7d2ff-42f2-4758-9464-88137c1da3a3.png?v=1710298015","url":"https:\/\/afsbio.com\/products\/kcnab1-polyclonal-antibody-e-ab-91124","provider":"AFSBio Inc.","version":"1.0","type":"link"}