{"product_id":"kcnd3-polyclonal-antibody-e-ab-61408","title":"KCND3 Polyclonal Antibody - E-AB-61408","description":"\u003cp\u003eKCND3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61408-60, E-AB-61408-120, E-AB-61408-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KCND3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: KCND3; BRGDA9; KCND3L; KCND3S; KSHIVB; KV4.3; SCA19; SCA22\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UK17\u003c\/p\u003e\n\n\u003cp\u003eBackground: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human KCND3 (NP_751948.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 71kDa\/73kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 73kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146165223603,"sku":"E-AB-61408-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146165256371,"sku":"E-AB-61408-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146165289139,"sku":"E-AB-61408-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7f5ca2ca-7fd5-4a18-8f19-67b553072b3a.png?v=1710291472","url":"https:\/\/afsbio.com\/products\/kcnd3-polyclonal-antibody-e-ab-61408","provider":"AFSBio Inc.","version":"1.0","type":"link"}