{"product_id":"kcnj1-polyclonal-antibody-e-ab-65587","title":"KCNJ1 Polyclonal Antibody - E-AB-65587","description":"\u003cp\u003eKCNJ1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-65587-60, E-AB-65587-120, E-AB-65587-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KCNJ1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: KCNJ1; KIR1.1; ROMK; ROMK1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P48048\u003c\/p\u003e\n\n\u003cp\u003eBackground: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human KCNJ1 (NP_000211.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42kDa\/44kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 45kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146376806579,"sku":"E-AB-65587-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146376839347,"sku":"E-AB-65587-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146376872115,"sku":"E-AB-65587-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b2159998-050a-4a5a-8eec-34db2ab030c8.png?v=1710294535","url":"https:\/\/afsbio.com\/products\/kcnj1-polyclonal-antibody-e-ab-65587","provider":"AFSBio Inc.","version":"1.0","type":"link"}