{"product_id":"kcnk10-polyclonal-antibody-e-ab-18165","title":"KCNK10 Polyclonal Antibody - E-AB-18165","description":"\u003cp\u003eKCNK10 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-18165-60, E-AB-18165-120, E-AB-18165-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KCNK10\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 2P domain potassium channel TREK2; K2p10.1; KCNK10; KCNKA; Outward rectifying potassium channel protein TREK 2; Outward rectifying potassium channel protein TREK-2; Potassium channel subfamily K member 10; Potassium channel TREK 2; TREK 2; TREK 2 K; TREK 2 K(+) channel subunit; TREK-2 K(+) channel subunit; TREK2; TWIK related K+ channel 2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P57789\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.\u003cbr\u003e\nKCNK10 (Potassium Two Pore Domain Channel Subfamily K Member 10) is a Protein Coding gene. Diseases associated with KCNK10 include Dentin Sensitivity. Among its related pathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK2.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.26 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human KCNK10\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:30-1:150, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130678018227,"sku":"E-AB-18165-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130678050995,"sku":"E-AB-18165-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130678083763,"sku":"E-AB-18165-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_801d0aef-e321-4eeb-a48a-8395e441d617.png?v=1709811264","url":"https:\/\/afsbio.com\/products\/kcnk10-polyclonal-antibody-e-ab-18165","provider":"AFSBio Inc.","version":"1.0","type":"link"}