{"product_id":"kcnn1-polyclonal-antibody-bt-ap10648","title":"KCNN1 Polyclonal Antibody - BT-AP10648","description":"\u003cp\u003eKCNN1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10648-20, BT-AP10648-50, BT-AP10648-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KCNN1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Small conductance calcium-activated potassium channel protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q92952; Mouse: Q9EQR3; Rat: P70606\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Small conductance calcium-activated potassium channel protein 1;SK1;SKCa 1;SKCa1;KCa2.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3780\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239191339187,"sku":"BT-AP10648-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239191371955,"sku":"BT-AP10648-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239191404723,"sku":"BT-AP10648-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_85bbfb70-f608-4667-a363-7afceffc37de.png?v=1769390362","url":"https:\/\/afsbio.com\/products\/kcnn1-polyclonal-antibody-bt-ap10648","provider":"AFSBio Inc.","version":"1.0","type":"link"}