{"product_id":"kd-validated-egfr-rabbit-polymab®-a24388pm","title":"[KD Validated] EGFR Rabbit PolymAb® - A24388PM","description":"\u003cp\u003e[KD Validated] EGFR Rabbit PolymAb®\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24388PM-20, A24388PM-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 44kDa\/69kDa\/77kDa\/134kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 145-175kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1956\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P00533\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA; epidermal growth factor receptor\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Tumor biomarkers, Signal Transduction, G protein signaling, Kinase, Tyrosine kinases, Phospholipase Signaling Pathway, ErbB-HER Signaling Pathway, Cell Biology \u0026amp; Developmental Biology, Growth factor, EGF, Immunology \u0026amp; Inflammation, IL-6 Receptor Signaling Pat\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: EGFR\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189849645235,"sku":"A24388PM-20","price":165.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189849678003,"sku":"A24388PM-100","price":431.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0feeb138-b069-4f80-a63b-35330c01cf40.png?v=1766436728","url":"https:\/\/afsbio.com\/products\/kd-validated-egfr-rabbit-polymab%c2%ae-a24388pm","provider":"AFSBio Inc.","version":"1.0","type":"link"}