{"product_id":"kdm4b-jmjd2b-rabbit-pab-a5824","title":"KDM4B\/JMJD2B Rabbit pAb - A5824","description":"\u003cp\u003eKDM4B\/JMJD2B Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A5824-20, A5824-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 122kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 150kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 23030\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O94953\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MRD65; JMJD2B; TDRD14B; KDM4B\/JMJD2B\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, DNA Damage Repair, Nuclear Receptor Signaling, Signal Transduction, Kinase, Serine threonine kinases, Cell Biology Developmental Biology, Cell Cycle, Immunology Inflammation.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: KDM4B\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189964398771,"sku":"A5824-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189964431539,"sku":"A5824-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b0ce69d0-dbde-4d3e-871b-09946dedbb8d.png?v=1766438953","url":"https:\/\/afsbio.com\/products\/kdm4b-jmjd2b-rabbit-pab-a5824","provider":"AFSBio Inc.","version":"1.0","type":"link"}