{"product_id":"kdm4d-polyclonal-antibody-bt-ap10663","title":"KDM4D Polyclonal Antibody - BT-AP10663","description":"\u003cp\u003eKDM4D Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10663-20, BT-AP10663-50, BT-AP10663-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,Belongs to the JHDM3 histone demethylase family.,Contains 1 JmjC domain.,Contains 1 JmjN domain.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KDM4D\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Lysine-specific demethylase 4D\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6B0I6; Mouse: Q3U2K5; Rat: A1A5Q5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Lysine-specific demethylase 4D;EC 1.14.11.-;JmjC domain-containing histone demethylation protein 3D;Jumonji domain-containing protein 2D\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 55693\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239192125619,"sku":"BT-AP10663-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239192158387,"sku":"BT-AP10663-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239192191155,"sku":"BT-AP10663-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_657b5d71-8880-47c9-a8cb-e2f062392667.png?v=1769390373","url":"https:\/\/afsbio.com\/products\/kdm4d-polyclonal-antibody-bt-ap10663","provider":"AFSBio Inc.","version":"1.0","type":"link"}