{"product_id":"kdm5b-polyclonal-antibody-bt-ap10665","title":"KDM5B Polyclonal Antibody - BT-AP10665","description":"\u003cp\u003eKDM5B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10665-20, BT-AP10665-50, BT-AP10665-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a lysine-specific histone demethylase that belongs to the jumonji\/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing resultsi n multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KDM5B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Lysine-specific demethylase 5B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UGL1; Mouse: Q80Y84\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Lysine-specific demethylase 5B;EC 1.14.11.-;Cancer\/testis antigen 31;CT31;Histone demethylase JARID1B;Jumonji\/ARID domain-containing protein 1B;PLU-1;Retinoblastoma-binding protein 2 homo\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10765\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239192354995,"sku":"BT-AP10665-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239192387763,"sku":"BT-AP10665-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239192420531,"sku":"BT-AP10665-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f8ec7046-7e23-4177-922a-f22ae8dad56e.png?v=1769390378","url":"https:\/\/afsbio.com\/products\/kdm5b-polyclonal-antibody-bt-ap10665","provider":"AFSBio Inc.","version":"1.0","type":"link"}