{"product_id":"kdr-monoclonal-antibody-bt-mca4633","title":"KDR Monoclonal Antibody - BT-MCA4633","description":"\u003cp\u003eKDR Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4633-50, BT-MCA4633-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KDR\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3C11A5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: KDR\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human KDR (AA: 1225-1356) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 151.5kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P35968\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FLK1, CD309, VEGFR, VEGFR2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3791\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238421553331,"sku":"BT-MCA4633-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238421586099,"sku":"BT-MCA4633-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5488055c-049f-44c8-8d33-8f2e62d7deec.png?v=1769380496","url":"https:\/\/afsbio.com\/products\/kdr-monoclonal-antibody-bt-mca4633","provider":"AFSBio Inc.","version":"1.0","type":"link"}