{"product_id":"ki2l2-polyclonal-antibody-ra32949","title":"KI2L2 Polyclonal Antibody - RA32949","description":"KI2L2 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA32949-50, RA32949-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several \"framework\" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the\n\nCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 3803\n\nProtein MW (KDa): 38\n\nSWISS: P43627\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120498663603,"sku":"RA32949-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120498696371,"sku":"RA32949-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ee509314-a798-4418-984c-a4368452a188.png?v=1773366691","url":"https:\/\/afsbio.com\/products\/ki2l2-polyclonal-antibody-ra32949","provider":"AFSBio Inc.","version":"1.0","type":"link"}