{"product_id":"ki2l4-polyclonal-antibody-ra32952","title":"KI2L4 Polyclonal Antibody - RA32952","description":"KI2L4 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA32952-50, RA32952-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 (KIR2DL4) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several \"framework\" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the\n\nCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 3805\n\nProtein MW (KDa): 41\n\nSWISS: Q99706\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120498860211,"sku":"RA32952-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120498892979,"sku":"RA32952-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3bcd68c5-6060-4ade-9358-a1cccb02d3aa.png?v=1773366695","url":"https:\/\/afsbio.com\/products\/ki2l4-polyclonal-antibody-ra32952","provider":"AFSBio Inc.","version":"1.0","type":"link"}