{"product_id":"kif-7-monoclonal-antibody-3f8-bt-mca0809","title":"Kif 7 Monoclonal Antibody (3F8) - BT-MCA0809","description":"\u003cp\u003eKif 7 Monoclonal Antibody (3F8)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0809-20, BT-MCA0809-50, BT-MCA0809-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KIF7\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P, IF, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Kinesin-like protein KIF7\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q2M1P5; Mouse: B7ZNG0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Kinesin-like protein KIF7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 374654; Mouse: 16576\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240043569331,"sku":"BT-MCA0809-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240043602099,"sku":"BT-MCA0809-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240043634867,"sku":"BT-MCA0809-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f5258c25-1c2f-42bb-8583-c0ac7ed52be8.png?v=1769402593","url":"https:\/\/afsbio.com\/products\/kif-7-monoclonal-antibody-3f8-bt-mca0809","provider":"AFSBio Inc.","version":"1.0","type":"link"}