{"product_id":"kinectin-1-polyclonal-antibody-bs67342","title":"Kinectin 1 Polyclonal Antibody-BS67342","description":"\u003cp\u003eKinectin 1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS67342-50, BS67342-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q86UP2\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/2000), IHC (1\/50 - 1\/200)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Kinectin 1 (KTN1) is an endoplasmic reticulum (ER)-enriched integral membrane protein that may be involved in the formation of ER sheets (reviewed in 1). Kinectin 1 binds the microtubule motor protein kinesin and acts as a membrane anchor for kinesin-based organelle trafficking. The interaction of kinesin with kinectin 1 has been shown to affect ER-supported focal adhesion assembly. Kinectin 1 has also been implicated in translation elongation, as an anchor for the elongation factor complex to the ER. Research investigators have shown that kinectin 1 expression is altered in multiple human pathologies, including breast cancer, hepatocellular carcinoma (HCC), Parkinson's disease , and the autoimmune syndrome Behçet's disease (BD)\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Kinectin 1 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Kinectin 1 expression in K562 (A), mouse testis (B) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 160 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CG1; KIAA0004; Kinectin; CG-1 antigen; Kinesin receptor\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide of human Kinectin 1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908750872755,"sku":"BS67342-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908750905523,"sku":"BS67342-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_51b8a4e2-e9be-4d27-8df8-187ca927b63a.jpg?v=1703006630","url":"https:\/\/afsbio.com\/products\/kinectin-1-polyclonal-antibody-bs67342","provider":"AFSBio Inc.","version":"1.0","type":"link"}