{"product_id":"kir3-1-polyclonal-antibody-ra26660","title":"KIR3.1 Polyclonal Antibody - RA26660","description":"KIR3.1 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA26660-50, RA26660-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: potassium voltage-gated channel subfamily J member 3 (KCNJ3) Homo sapiens Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, at\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: KCNJ3; GIRK1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K (+) channel Kir3.1; Potassium channel; inwardly rectifying subfamily J member 3\n\nApplications: WB; IF\/ICC; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 3760\n\nProtein MW (KDa): 56\n\nSWISS: P48549\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121371242675,"sku":"RA26660-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121371275443,"sku":"RA26660-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a3138cfe-1b19-40d5-a7e6-4672b02ff71d.png?v=1773346901","url":"https:\/\/afsbio.com\/products\/kir3-1-polyclonal-antibody-ra26660","provider":"AFSBio Inc.","version":"1.0","type":"link"}