{"product_id":"kirr2-polyclonal-antibody-bt-ap10707","title":"KIRR2 Polyclonal Antibody - BT-AP10707","description":"\u003cp\u003eKIRR2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10707-20, BT-AP10707-50, BT-AP10707-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KIRREL2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Kin of IRRE-like protein 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6UWL6; Mouse: Q7TSU7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Kin of IRRE-like protein 2;Kin of irregular chiasm-like protein 2;Nephrin-like protein 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 84063\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239194452147,"sku":"BT-AP10707-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239194484915,"sku":"BT-AP10707-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239194517683,"sku":"BT-AP10707-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1a072f67-cc79-41cb-b599-770447f92326.png?v=1769390408","url":"https:\/\/afsbio.com\/products\/kirr2-polyclonal-antibody-bt-ap10707","provider":"AFSBio Inc.","version":"1.0","type":"link"}