{"product_id":"kirrel2-polyclonal-antibody-e-ab-66011","title":"KIRREL2 Polyclonal Antibody - E-AB-66011","description":"\u003cp\u003eKIRREL2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66011-60, E-AB-66011-120, E-AB-66011-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KIRREL2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: KIRREL2; FILTRIN; NEPH3; NLG1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q6UWL6\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human KIRREL2 (NP_954649.3).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 23kDa\/61kDa\/67kDa\/75kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 95kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146399678643,"sku":"E-AB-66011-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146399711411,"sku":"E-AB-66011-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146399744179,"sku":"E-AB-66011-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_04a8252a-daff-44b5-9303-f7abf171a9ba.png?v=1710294885","url":"https:\/\/afsbio.com\/products\/kirrel2-polyclonal-antibody-e-ab-66011","provider":"AFSBio Inc.","version":"1.0","type":"link"}