{"product_id":"klf1-polyclonal-antibody-e-ab-19799","title":"KLF1 Polyclonal Antibody - E-AB-19799","description":"\u003cp\u003eKLF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19799-60, E-AB-19799-120, E-AB-19799-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KLF1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CDAN4; EKLF; EKLF PEN; Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor); Erythroid krueppel-like transcription factor; Erythroid Kruppel like factor; Erythroid specific transcription factor EKLF; HBFQTL6; Human erythroid-specific transcription factor EKLF mRNA complete cds; INLU; Klf1; KLF1; Krueppel-like factor 1; Kruppel like factor 1 (erythroid)\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q13351\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.96 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human KLF1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:100, ELISA 1:2000-1:5000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133416800435,"sku":"E-AB-19799-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133416833203,"sku":"E-AB-19799-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133416865971,"sku":"E-AB-19799-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2fb92f4a-68bc-4933-9797-420071ee0c90.png?v=1709898729","url":"https:\/\/afsbio.com\/products\/klf1-polyclonal-antibody-e-ab-19799","provider":"AFSBio Inc.","version":"1.0","type":"link"}