{"product_id":"klf8-polyclonal-antibody-bt-ap04843","title":"KLF8 Polyclonal Antibody - BT-AP04843","description":"\u003cp\u003eKLF8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04843-20, BT-AP04843-50, BT-AP04843-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: KLF8 encodes Kruppel like factor 8 which is a member of the Sp\/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KLF8\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: KLF8 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 39314\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O95600; Mouse: Q8BLM0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KLF8; BKLF3; ZNF741; Krueppel-like factor 8; Basic krueppel-like factor 3; Zinc finger protein 741\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 11279\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239650549939,"sku":"BT-AP04843-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239650582707,"sku":"BT-AP04843-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239650615475,"sku":"BT-AP04843-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e434336d-fa96-4b64-90b4-fef37aca0866.png?v=1769397570","url":"https:\/\/afsbio.com\/products\/klf8-polyclonal-antibody-bt-ap04843","provider":"AFSBio Inc.","version":"1.0","type":"link"}