{"product_id":"klhl1-monoclonal-antibody-bt-mca4706","title":"KLHL1 Monoclonal Antibody - BT-MCA4706","description":"\u003cp\u003eKLHL1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4706-50, BT-MCA4706-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KLHL1\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3A8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: KLHL1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human KLHL1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 82kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9NR64\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MRP2, FLJ30047, KIAA1490, KLHL1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 57626\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238610428083,"sku":"BT-MCA4706-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238610460851,"sku":"BT-MCA4706-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cc43a891-6a01-4113-ad27-bacdf94f2780.png?v=1769383051","url":"https:\/\/afsbio.com\/products\/klhl1-monoclonal-antibody-bt-mca4706","provider":"AFSBio Inc.","version":"1.0","type":"link"}