{"product_id":"klhl12-monoclonal-antibody-bt-mca3618","title":"KLHL12 Monoclonal Antibody - BT-MCA3618","description":"\u003cp\u003eKLHL12 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3618-50, BT-MCA3618-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KLHL12\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2G2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: KLHL12\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human KLHL12 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 63kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q53G59\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DKIR, C3IP1, FLJ27152, KLHL12\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 59349\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238617669811,"sku":"BT-MCA3618-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238617702579,"sku":"BT-MCA3618-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4b7003ea-7512-4c5c-8427-d87b112a215c.png?v=1769383115","url":"https:\/\/afsbio.com\/products\/klhl12-monoclonal-antibody-bt-mca3618","provider":"AFSBio Inc.","version":"1.0","type":"link"}