{"product_id":"klhl12-monoclonal-antibody-ra11576","title":"KLHL12 Monoclonal Antibody - RA11576","description":"KLHL12 Monoclonal Antibody\n\nSize: 50μL, 100μL\n\nCatalogue Numbers: RA11576-50, RA11576-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: kelch like family member 12 (KLHL12) Homo sapiens This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],\n\nCondition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.\n\nStorage Instructions: -20°C\/1 year\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human\n\nGeneID (Human): 59349\n\nSWISS: Q53G59\n\nSource: Mouse\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118980751539,"sku":"RA11576-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118980784307,"sku":"RA11576-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_81444709-b033-4d44-a337-173428bdf3c0.png?v=1773343883","url":"https:\/\/afsbio.com\/products\/klhl12-monoclonal-antibody-ra11576","provider":"AFSBio Inc.","version":"1.0","type":"link"}