{"product_id":"klot-polyclonal-antibody-bt-ap10732","title":"KLOT Polyclonal Antibody - BT-AP10732","description":"\u003cp\u003eKLOT Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10732-20, BT-AP10732-50, BT-AP10732-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Developmental biology; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Klotho\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UEF7; Mouse: O35082; Rat: Q9Z2Y9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Klotho;EC 3.2.1.31 [Cleaved into: Klotho peptide]\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9365\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239196156083,"sku":"BT-AP10732-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239196188851,"sku":"BT-AP10732-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239196221619,"sku":"BT-AP10732-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2213614e-970e-4734-ac8b-1e0a5c6055e1.png?v=1769390432","url":"https:\/\/afsbio.com\/products\/klot-polyclonal-antibody-bt-ap10732","provider":"AFSBio Inc.","version":"1.0","type":"link"}