{"product_id":"ko-validated-dnmt3a-polyclonal-antibody-e-ab-67769","title":"(KO Validated) DNMT3A Polyclonal Antibody - E-AB-67769","description":"\u003cp\u003e(KO Validated) DNMT3A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67769-60, E-AB-67769-120, E-AB-67769-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DNMT3A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNMT3A\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9Y6K1\u003c\/p\u003e\n\n\u003cp\u003eBackground: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human DNMT3A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 16kDa\/81kDa\/101kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 140kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146456826035,"sku":"E-AB-67769-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146456858803,"sku":"E-AB-67769-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146456891571,"sku":"E-AB-67769-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c2ca3733-e4c4-4ba8-aea1-7cf5dbf1414f.png?v=1710295898","url":"https:\/\/afsbio.com\/products\/ko-validated-dnmt3a-polyclonal-antibody-e-ab-67769","provider":"AFSBio Inc.","version":"1.0","type":"link"}