{"product_id":"ko-validated-eef2k-rabbit-pab-a5404","title":"[KO Validated] EEF2K Rabbit pAb - A5404","description":"\u003cp\u003e[KO Validated] EEF2K Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A5404-20, A5404-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 82kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 110kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 29904\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O00418\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: eEF-2K; CaMKIII; HSU93850; 2K\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Translation Control, Protein phosphorylation, Signal Transduction, Kinase, Serine threonine kinases, MAPK-Erk Signaling Pathway, Endocrine Metabolism, AMPK Signaling Pathway, Neuroscience, Calcium Signaling.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: EEF2K\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189942542515,"sku":"A5404-20","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189942575283,"sku":"A5404-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_2516ad5b-cb6a-4a5b-9815-e45225f4c34d.png?v=1766438535","url":"https:\/\/afsbio.com\/products\/ko-validated-eef2k-rabbit-pab-a5404","provider":"AFSBio Inc.","version":"1.0","type":"link"}