{"product_id":"ko-validated-egfr-polyclonal-antibody-e-ab-63241","title":"(KO Validated) EGFR Polyclonal Antibody - E-AB-63241","description":"\u003cp\u003e(KO Validated) EGFR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63241-60, E-AB-63241-120, E-AB-63241-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: EGFR\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P00533\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human EGFR (NP_005219.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44kDa\/69kDa\/77kDa\/134kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 175kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146282565811,"sku":"E-AB-63241-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146282598579,"sku":"E-AB-63241-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146282631347,"sku":"E-AB-63241-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_789eb266-de50-4709-b573-8c74695833a8.png?v=1710292966","url":"https:\/\/afsbio.com\/products\/ko-validated-egfr-polyclonal-antibody-e-ab-63241","provider":"AFSBio Inc.","version":"1.0","type":"link"}