{"product_id":"ko-validated-hur-elavl1-polyclonal-antibody-e-ab-60367","title":"(KO Validated) HuR \/ ELAVL1 Polyclonal Antibody - E-AB-60367","description":"\u003cp\u003e(KO Validated) HuR \/ ELAVL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60367-60, E-AB-60367-120, E-AB-60367-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HuR \/ ELAVL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ELAV1; HUR; Hua; MelG; HuR \/ ELAVL1; ELAVL1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15717\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human HuR \/ ELAVL1 (NP_001410.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:100-1:200   IF \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36kDa\/38kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 37kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146053615795,"sku":"E-AB-60367-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146053648563,"sku":"E-AB-60367-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146053681331,"sku":"E-AB-60367-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9ad1bc84-5a78-4e86-9b01-b5311be67991.png?v=1710290641","url":"https:\/\/afsbio.com\/products\/ko-validated-hur-elavl1-polyclonal-antibody-e-ab-60367","provider":"AFSBio Inc.","version":"1.0","type":"link"}