{"product_id":"ko-validated-map2k7-polyclonal-antibody-e-ab-60668","title":"(KO Validated) MAP2K7 Polyclonal Antibody - E-AB-60668","description":"\u003cp\u003e(KO Validated) MAP2K7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60668-60, E-AB-60668-120, E-AB-60668-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: MAP2K7\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MAP2K7; JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4; MEK7; MKK7\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O14733\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8\/JNK1 and MAPK9\/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1\/MEKK1, MAP3K2\/MEKK2, MAP3K3\/MEKK5, and MAP4K2\/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human MAP2K7 (NP_660186.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136826343603,"sku":"E-AB-60668-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136826376371,"sku":"E-AB-60668-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136826409139,"sku":"E-AB-60668-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_674a3fc2-600e-4f8f-b203-40184d6041aa.png?v=1709992352","url":"https:\/\/afsbio.com\/products\/ko-validated-map2k7-polyclonal-antibody-e-ab-60668","provider":"AFSBio Inc.","version":"1.0","type":"link"}