{"product_id":"ko-validated-nf-kb-p65-polyclonal-antibody-e-ab-93366","title":"(KO Validated) NF-kB p65 Polyclonal Antibody - E-AB-93366","description":"\u003cp\u003e(KO Validated) NF-kB p65 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93366-60, E-AB-93366-120, E-AB-93366-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NF-kB p65\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RELA; NFKB3; p65; transcription factor p65\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q04206\u003c\/p\u003e\n\n\u003cp\u003eBackground: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human NF-kB p65\/RelA\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 58kDa\/59kDa\/60kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 65KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146695377075,"sku":"E-AB-93366-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146695409843,"sku":"E-AB-93366-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146695442611,"sku":"E-AB-93366-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8eb9dceb-1f0d-42a8-ab2a-ed1889c4edc6.png?v=1710300320","url":"https:\/\/afsbio.com\/products\/ko-validated-nf-kb-p65-polyclonal-antibody-e-ab-93366","provider":"AFSBio Inc.","version":"1.0","type":"link"}