{"product_id":"ko-validated-nox4-polyclonal-antibody-e-ab-64074","title":"(KO Validated) NOX4 Polyclonal Antibody - E-AB-64074","description":"\u003cp\u003e(KO Validated) NOX4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64074-60, E-AB-64074-120, E-AB-64074-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NOX4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NOX4; KOX; KOX-1; RENOX\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NPH5\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human NOX4 (NP_058627.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 6kDa\/25-31kDa\/58-66kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 75kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146311729331,"sku":"E-AB-64074-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146311762099,"sku":"E-AB-64074-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146311794867,"sku":"E-AB-64074-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_32d419f6-64ba-44ff-a0ab-0e6f420bc8f5.png?v=1710293424","url":"https:\/\/afsbio.com\/products\/ko-validated-nox4-polyclonal-antibody-e-ab-64074","provider":"AFSBio Inc.","version":"1.0","type":"link"}