{"product_id":"ko-validated-por-polyclonal-antibody-e-ab-62876","title":"(KO Validated) POR Polyclonal Antibody - E-AB-62876","description":"\u003cp\u003e(KO Validated) POR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62876-60, E-AB-62876-120, E-AB-62876-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: POR\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: POR; CPR; CYPOR; P450R\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P16435\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human POR (NP_000932.3).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:50-1:100   IF \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 76kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 77kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146266476723,"sku":"E-AB-62876-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146266509491,"sku":"E-AB-62876-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146266542259,"sku":"E-AB-62876-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_77faa041-32f7-4013-a2aa-42645bd7a7d7.png?v=1710292659","url":"https:\/\/afsbio.com\/products\/ko-validated-por-polyclonal-antibody-e-ab-62876","provider":"AFSBio Inc.","version":"1.0","type":"link"}