{"product_id":"ko-validated-tdp2-polyclonal-antibody-e-ab-92386","title":"(KO Validated) TDP2 Polyclonal Antibody - E-AB-92386","description":"\u003cp\u003e(KO Validated) TDP2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92386-60, E-AB-92386-120, E-AB-92386-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TDP2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TDP2; AD022; EAP2; EAPII; TTRAP; dJ30M3.3; hTDP2; tyrosyl-DNA phosphodiesterase 2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O95551\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TDP2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 32kDa\/40kDa\/44kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 41KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146633674931,"sku":"E-AB-92386-60","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146633707699,"sku":"E-AB-92386-120","price":504.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146633740467,"sku":"E-AB-92386-200","price":812.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_babea790-5da3-4cdd-a7af-d89be8846900.png?v=1710298946","url":"https:\/\/afsbio.com\/products\/ko-validated-tdp2-polyclonal-antibody-e-ab-92386","provider":"AFSBio Inc.","version":"1.0","type":"link"}