{"product_id":"kox17-k22-polyclonal-antibody-bs1938","title":"KOX17 (K22) Polyclonal Antibody-BS1938","description":"\u003cp\u003eKOX17 (K22) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1938-50, BS1938-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P17028\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eBackground: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF191 (Zinc finger protein 191), also known as ZNF24, KOX17, ZSCAN3 or RSG-A, is a 368 amino acid nuclear protein that belongs to the Krueppel C2H2-type zinc-finger protein family. Expressed in tissues throughout the body with the exception of heart, ZNF191 functions as a transcriptional repressor for a variety of proteins, such as VEGF (vascular endothelial growth factor), and is thought to be important for early embryonic development and cell proliferation. ZNF191 contains four C2H2-type zinc fingers and one SCAN box domain and, upon DNA damage, may be phosphorylated by ATM or ATR.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: KOX17 (K22) polyclonal antibody detects endogenous levels of KOX17 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of KOX17 (K22) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: Hela whole cell lysate (40ug)\u003cbr\u003e\nLane 2: HEK293T whole cell lysate (40ug)\u003cbr\u003e\nLane 3: A549 whole cell lysate (40ug)\u003cbr\u003e\nLane 4: U-87MG whole cell lysate (40ug)\u003cbr\u003e\nLane 5: The Brain tissue lysate of Rat (10ug)\u003cbr\u003e\nLane 6: PC12 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of KOX17 (K22) pAb in paraffin-embedded human heart tissue.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: KOX17; Retinoic acid suppression protein A; RSG A; RSGA; Zfp191; Zinc finger and SCAN domain containing protein 3; Zinc finger protein 191; Zinc finger protein 24; Zinc finger protein KOX17; ZNF 24; ZNF191; ZSCAN 3; ZSCAN3;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the N-terminus of Human KOX17.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953217409203,"sku":"BS1938-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953217441971,"sku":"BS1938-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4bd5e703-2670-4c5e-9fb3-364d6bdbe812.jpg?v=1705056960","url":"https:\/\/afsbio.com\/products\/kox17-k22-polyclonal-antibody-bs1938","provider":"AFSBio Inc.","version":"1.0","type":"link"}