{"product_id":"ku-80-acetyl-lys565-rabbit-pab-es15226","title":"Ku-80 (Acetyl Lys565) rabbit pAb - ES15226","description":"\u003cp\u003eKu-80 (Acetyl Lys565) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES15226-50, ES15226-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: X-ray repair cross-complementing protein 5 (EC 3.6.4.-; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; IF; WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p 1:50-200, WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human Ku-80 (Acetyl-Lys565)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 82kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7520\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P13010\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Nucleus, nucleolus. Chromosome.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202413551795,"sku":"ES15226-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202413584563,"sku":"ES15226-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_8ecc0745-d06f-41df-8780-3dc5e430492a.png?v=1767128633","url":"https:\/\/afsbio.com\/products\/ku-80-acetyl-lys565-rabbit-pab-es15226","provider":"AFSBio Inc.","version":"1.0","type":"link"}