{"product_id":"kv1-1-polyclonal-antibody-bt-ap04904","title":"KV1.1 Polyclonal Antibody - BT-AP04904","description":"\u003cp\u003eKV1.1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04904-20, BT-AP04904-50, BT-AP04904-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: KCNA1 encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. Potassium voltage-gated channel subfamily A member 1 has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KCNA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: KV1.1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 56542\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q09470; Mouse: P16388; Rat: P10499\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3736; Mouse: 16485; Rat: 24520\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239653662899,"sku":"BT-AP04904-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239653695667,"sku":"BT-AP04904-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239653728435,"sku":"BT-AP04904-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_98a20e66-a62a-4d6b-9953-55973d26fe1d.png?v=1769397623","url":"https:\/\/afsbio.com\/products\/kv1-1-polyclonal-antibody-bt-ap04904","provider":"AFSBio Inc.","version":"1.0","type":"link"}