{"product_id":"kv1-1-potassium-channel-polyclonal-antibody-bt-ap10783","title":"Kv1.1 potassium channel Polyclonal Antibody - BT-AP10783","description":"\u003cp\u003eKv1.1 potassium channel Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10783-20, BT-AP10783-50, BT-AP10783-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KCNA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Potassium voltage-gated channel subfamily A member 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q09470; Mouse: P16388; Rat: P10499\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Potassium voltage-gated channel subfamily A member 1;Voltage-gated K;+ channel HuKI;Voltage-gated potassium channel HBK1;Voltage-gated potassium channel subunit Kv1.1; KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K;+ channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3736\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239198777523,"sku":"BT-AP10783-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239198810291,"sku":"BT-AP10783-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239198843059,"sku":"BT-AP10783-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2c1df39b-1915-4288-a8b4-c4a6e9c8bec8.png?v=1769390478","url":"https:\/\/afsbio.com\/products\/kv1-1-potassium-channel-polyclonal-antibody-bt-ap10783","provider":"AFSBio Inc.","version":"1.0","type":"link"}