{"product_id":"kv4-2-polyclonal-antibody-bt-ap04923","title":"Kv4.2 Polyclonal Antibody - BT-AP04923","description":"\u003cp\u003eKv4.2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04923-20, BT-AP04923-50, BT-AP04923-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCND2 encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KCND2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Kv4.2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 70577\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NZV8; Mouse: Q9Z0V2; Rat: Q63881\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KCND2; KIAA1044; Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel subunit Kv4.2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3751; Mouse: 16508; Rat: 65180\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239654351027,"sku":"BT-AP04923-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239654383795,"sku":"BT-AP04923-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239654416563,"sku":"BT-AP04923-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_34f429c0-ee34-4ed5-bc85-484f149add9a.png?v=1769397634","url":"https:\/\/afsbio.com\/products\/kv4-2-polyclonal-antibody-bt-ap04923","provider":"AFSBio Inc.","version":"1.0","type":"link"}