{"product_id":"l-plastin-lcp1-rabbit-pab-a5561","title":"L-Plastin\/LCP1 Rabbit pAb - A5561","description":"\u003cp\u003eL-Plastin\/LCP1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A5561-20, A5561-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.) . However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IP, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 70kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 70kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3936\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P13796\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN; L-Plastin\/LCP1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Protein phosphorylation, Cancer, Tumor immunology, Tumor-associated antigens, Tumor biomarkers, Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Immunology Inflammation.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: LCP1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189949227187,"sku":"A5561-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189949259955,"sku":"A5561-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c89b7f3f-76f7-4c95-bd08-6c5ee910400f.png?v=1766438675","url":"https:\/\/afsbio.com\/products\/l-plastin-lcp1-rabbit-pab-a5561","provider":"AFSBio Inc.","version":"1.0","type":"link"}