{"product_id":"lamin-b1-rabbit-pab-ea041","title":"Lamin B1 Rabbit pAb - EA041","description":"\u003cp\u003eLamin B1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EA041-50, EA041-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: ADLD, LMB1, LMNB1, MGC111419, OTTHUMP00000159218\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000-3, 000  IHC: 1:500-1, 000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 68, 45kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 4001\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P20700\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Mitochondrion inner membrane\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201968824499,"sku":"EA041-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201968857267,"sku":"EA041-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_1ccb3a92-0d4b-4fd5-b708-d7a39ed0fa0c.png?v=1767119082","url":"https:\/\/afsbio.com\/products\/lamin-b1-rabbit-pab-ea041","provider":"AFSBio Inc.","version":"1.0","type":"link"}