{"product_id":"larg-rabbit-pab-es5333","title":"LARG rabbit pAb - ES5333","description":"\u003cp\u003eLARG rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5333-50, ES5333-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid\/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 173kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 23365\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9NZN5\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Membrane. Translocated to the membrane upon stimulation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202242142387,"sku":"ES5333-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202242175155,"sku":"ES5333-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3743b724-018a-4ac3-8413-22cb3f369c61.png?v=1767124937","url":"https:\/\/afsbio.com\/products\/larg-rabbit-pab-es5333","provider":"AFSBio Inc.","version":"1.0","type":"link"}