{"product_id":"lasp-1-polyclonal-antibody-bt-ap04955","title":"LASP-1 Polyclonal Antibody - BT-AP04955","description":"\u003cp\u003eLASP-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04955-20, BT-AP04955-50, BT-AP04955-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The LIM and SH3 protein 1 is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LASP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LASP-1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 29717\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14847; Mouse: Q61792; Rat: Q99MZ8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LASP1; MLN50; LIM and SH3 domain protein 1; LASP-1; Metastatic lymph node gene 50 protein; MLN 50\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3927; Mouse: 16796; Rat: 29278\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239657791667,"sku":"BT-AP04955-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239657824435,"sku":"BT-AP04955-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239657857203,"sku":"BT-AP04955-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b6332790-e9b1-401a-8af8-a84e27637123.png?v=1769397677","url":"https:\/\/afsbio.com\/products\/lasp-1-polyclonal-antibody-bt-ap04955","provider":"AFSBio Inc.","version":"1.0","type":"link"}