{"product_id":"lat-phospho-tyr171-rabbit-polyclonal-antibody-bt-ap11002","title":"LAT (Phospho-Tyr171) Rabbit Polyclonal Antibody - BT-AP11002","description":"\u003cp\u003eLAT (Phospho-Tyr171) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11002-20, BT-AP11002-50, BT-AP11002-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is phosphorylated by ZAP-70\/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation| this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LAT\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LAT\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O43561; Mouse: O54957; Rat: O70601\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LAT;Tyr171; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 27040; Mouse: 16797; Rat: 81511\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239002202291,"sku":"BT-AP11002-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239002235059,"sku":"BT-AP11002-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239002267827,"sku":"BT-AP11002-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0723c72e-f353-4e8f-8162-c05a74f409f1.png?v=1769387811","url":"https:\/\/afsbio.com\/products\/lat-phospho-tyr171-rabbit-polyclonal-antibody-bt-ap11002","provider":"AFSBio Inc.","version":"1.0","type":"link"}