{"product_id":"lat-polyclonal-antibody-e-ab-92662","title":"LAT Polyclonal Antibody - E-AB-92662","description":"\u003cp\u003eLAT Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92662-60, E-AB-92662-120, E-AB-92662-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: LAT\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: LAT; LAT1; pp36; IMD52\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O43561\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is phosphorylated by ZAP-70\/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human LAT\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 24kDa\/27kDa\/28kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146648944819,"sku":"E-AB-92662-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146648977587,"sku":"E-AB-92662-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146649010355,"sku":"E-AB-92662-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9dbecb9b-baf5-4f54-960d-9a2204f01586.png?v=1710299318","url":"https:\/\/afsbio.com\/products\/lat-polyclonal-antibody-e-ab-92662","provider":"AFSBio Inc.","version":"1.0","type":"link"}