{"product_id":"lax1-polyclonal-antibody-ra33052","title":"LAX1 Polyclonal Antibody - RA33052","description":"\u003cp\u003eLAX1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA33052-50, RA33052-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and BCR (B-cell antigen receptor) -mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 54900\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 43\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8IWV1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120502300851,"sku":"RA33052-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120502333619,"sku":"RA33052-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_221a657a-48c1-44e1-a6d4-fc92ef384012.png?v=1773366768","url":"https:\/\/afsbio.com\/products\/lax1-polyclonal-antibody-ra33052","provider":"AFSBio Inc.","version":"1.0","type":"link"}