{"product_id":"lc3-a-b-rabbit-polyclonal-antibody-bt-ap11012","title":"LC3 A\/B Rabbit Polyclonal Antibody - BT-AP11012","description":"\u003cp\u003eLC3 A\/B Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11012-20, BT-AP11012-50, BT-AP11012-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Probably involved in formation of autophagosomal vacuoles (autophagosomes).|PTM:The precursor molecule is cleaved by APG4B\/ATG4B to form the cytosolic form| LC3-I. This is activated by APG7L\/ATG7| transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form| LC3-II.|Belongs to the MAP1 LC3 family.|subcellular location:LC3-II binds to the autophagic membranes.|subunit:3 different light chains| LC1| LC2 and LC3| can associate with MAP1A and MAP1B proteins.|tissue specificity:Most abundant in heart| brain| liver| skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.|\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Metabolism; Signal transduction; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LC3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LC3 A\/B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 13310\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H492\/Q9GZQ8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LC3 A\/B\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238920872115,"sku":"BT-AP11012-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238920904883,"sku":"BT-AP11012-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238920937651,"sku":"BT-AP11012-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ae9cb14f-79f4-4961-a8bc-9738ae92f093.png?v=1769386712","url":"https:\/\/afsbio.com\/products\/lc3-a-b-rabbit-polyclonal-antibody-bt-ap11012","provider":"AFSBio Inc.","version":"1.0","type":"link"}