{"product_id":"lc3-a-b-rabbit-polyclonal-antibody-ra26827","title":"LC3 A\/B Rabbit Polyclonal Antibody - RA26827","description":"\u003cp\u003eLC3 A\/B Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA26827-50, RA26827-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Probably involved in formation of autophagosomal vacuoles (autophagosomes) .,PTM:The precursor molecule is cleaved by APG4B\/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L\/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:LC3-II binds to the autophagic membranes.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.,tissue specificity:Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB: 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 14,16\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9H492\/Q9GZQ8\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120385188019,"sku":"RA26827-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120385220787,"sku":"RA26827-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5a4285b3-8632-4df8-8105-feed25e57d95.png?v=1773364395","url":"https:\/\/afsbio.com\/products\/lc3-a-b-rabbit-polyclonal-antibody-ra26827","provider":"AFSBio Inc.","version":"1.0","type":"link"}