{"product_id":"ldhb-polyclonal-antibody-bt-ap10872","title":"LDHB Polyclonal Antibody - BT-AP10872","description":"\u003cp\u003eLDHB Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10872-20, BT-AP10872-50, BT-AP10872-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LDHB\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: L-lactate dehydrogenase B chain\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P07195; Mouse: P16125; Rat: P42123\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: L-lactate dehydrogenase B chain;LDH-B;EC 1.1.1.27;LDH heart subunit;LDH-H;Renal carcinoma antigen NY-REN-46\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3945\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239201824947,"sku":"BT-AP10872-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239201857715,"sku":"BT-AP10872-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239201890483,"sku":"BT-AP10872-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_79067835-3426-4ee1-abe8-a2f6a4c57be3.png?v=1769390524","url":"https:\/\/afsbio.com\/products\/ldhb-polyclonal-antibody-bt-ap10872","provider":"AFSBio Inc.","version":"1.0","type":"link"}