{"product_id":"ldoc1-polyclonal-antibody-bt-ap04990","title":"LDOC1 Polyclonal Antibody - BT-AP04990","description":"\u003cp\u003eLDOC1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04990-20, BT-AP04990-50, BT-AP04990-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The leucine zipper down-regulated in cancer 1 encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and\/or progression of some cancers.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LDOC1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: LDOC1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 16968\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O95751; Mouse: Q7TPY9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23641; Mouse: 434784\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239660806323,"sku":"BT-AP04990-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239660839091,"sku":"BT-AP04990-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239660871859,"sku":"BT-AP04990-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_409ea172-d561-4a44-a82a-c2191fd1a859.png?v=1769397716","url":"https:\/\/afsbio.com\/products\/ldoc1-polyclonal-antibody-bt-ap04990","provider":"AFSBio Inc.","version":"1.0","type":"link"}