{"product_id":"legumain-polyclonal-antibody-bs65876","title":"Legumain Polyclonal Antibody-BS65876","description":"\u003cp\u003eLegumain Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65876-50, BS65876-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q99538\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Dog, Cow, Horse,\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: Flow-Cyt=1ug\/test\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal\/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008].\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -49°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Legumain Polyclonal Antibody detects endogenous levels of Legumain protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~46kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: AEP;  Asparaginyl endopeptidase;  EC 3.4.22.34;  LGMN;  LGMN1;  Protease, cysteine 1;  protease, cysteine, 1 (legumain);  PRSC1;  LGMN_HUMAN.\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human Legumain:201-300\/433\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42899707101363,"sku":"BS65876-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42899707134131,"sku":"BS65876-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5ccb768b-66a7-418f-ac9a-0ef317d3a404.jpg?v=1702661378","url":"https:\/\/afsbio.com\/products\/legumain-polyclonal-antibody-bs65876","provider":"AFSBio Inc.","version":"1.0","type":"link"}