{"product_id":"li-cadherin-t363-polyclonal-antibody-bs2396","title":"LI-cadherin (T363) Polyclonal Antibody-BS2396","description":"\u003cp\u003eLI-cadherin (T363) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2396-50, BS2396-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q12864\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200 \u003cbr\u003e\nIF: 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin β, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: LI-cadherin (T363) polyclonal antibody detects endogenous levels of LI-cadherin protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~90 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of LI-cadherin (T363) Antibody at 1:2000 dilution\u003cbr\u003e\n Lane 1: SGC7901 whole cell lysate (40ug)\u003cbr\u003e\n Lane 2: HCT116 whole cell lysate (40ug)\u003cbr\u003e\n Lane 3: CT26 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of LI-cadherin (T363) pAb in paraffin-embedded human colon carcinoma tissue at 1:5000. cell membrane staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase., Immunohistochemistry (IHC) analyzes of LI-cadherin (T363) pAb in paraffin-embedded human rectum carcinoma tissue at 1:5000. cell membrane staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CDH17; Cadherin-17;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 350-400 of Human LI-cadherin.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993795268787,"sku":"BS2396-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993795301555,"sku":"BS2396-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f68450df-fcf3-491d-9d7c-37a51fe56618.jpg?v=1706183645","url":"https:\/\/afsbio.com\/products\/li-cadherin-t363-polyclonal-antibody-bs2396","provider":"AFSBio Inc.","version":"1.0","type":"link"}